IRRAflow System Confirmed to More Effectively Remove Collected Blood and Reduce Catheter Infection Rates than Passive Drainage in Head-to-Head Analysis

Stockholm, February 13, 2023 – IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced that the publication of the first comparative study detailing the use of the company’s novel IRRAflow system.  This study, which was conducted under the guidance of Dr. Adnan Siddiqui and the team from the Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, one of the world’s leading centers for neurosurgical innovation, was published in the peer-reviewed Operative Neurosurgery medical journal.  The manuscript concludes that IRRAS’ IRRAflow system when used for the treatment of chronic subdural hematomas (cSDH) results in favorable clinical outcomes, low complication and revision rates, faster clearance of collected blood, and reduced rates of catheter infections compared to passive drainage using an external ventricular drain (EVD).

The manuscript, titled “Use of Novel Automated Active Irrigation With Drainage Versus Passive Drainage Alone for Chronic Subdural Hematoma—A Propensity Score-Matched Comparative Study With Volumetric Analysis,” retrospectively analyzed the treatment of 55 patients, 21 treated with IRRAflow and 34 treated with passive drainage, that underwent propensity score matching to ensure appropriate similarities in patient demographics, baseline comorbidities, and hematoma volume.

After the completion of the analysis, the surgeons found that the use of IRRAflow resulted in a statistically significant higher rate of hematoma clearance (0.5 ± 0.4 mL/day with IRRAflow vs. 0.4 ± 0.5 mL/day with passive drainage) and a statistically significant reduction in catheter-related infections.  Additionally, in the subgroup analysis that looked procedures that were performed using a burrhole alone, treatment with IRRAflow also resulted in significantly lower hematoma expansion at discharge and significantly improved brain expansion.

Furthermore, the data from this clinical study showed that the use of IRRAflow resulted in a nonsignificant reduction in duration of catheter placement (3.7 ± 2.2 with IRRAflow vs. 4.4 ± 4.1 with passive drainage), total hospital length of stay (6.8 ± 3.0 with IRRAflow vs. 10.6 ± 16.2  with passive drainage), and rate of seizure activity (0 patients with IRRAflow vs. 3 patients with passive drainage), each suggesting a trend that may have shown significance with a larger sample size.

A chronic subdural hematoma is a collection of blood and blood breakdown products between the surface of the brain and its outer layer that generally occurs after head trauma in an older patient.  As the world’s population progressively ages, the increasing incidence of cSDH will be a burden to patients and a future challenge for neurosurgical clinics.[1] The incidence of chronic subdural hematomas (CSDH) ranges from 1.72 to 20.6 per 100,000 persons per year and is projected to become the most common cranial neurosurgical condition among adults by the year 2030.[2],[3]

"This recently published clinical data confirms the positive impact that IRRAflow can have on the lives of patients suffering from intracranial bleeding," said Will Martin, President and Chief Executive Officer of IRRAS. "This study is a critical next step in the growing pool of clinical evidence that demonstrates the impact of IRRAflow by providing head-to-head data that confirms that IRRAflow's combination of irrigation and drainage results in both more effective blood removal and safer clinical outcomes than traditional treatment methods."

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on February 13, 2023, at 8:30 (CET).

[1] Rauhala M, Luoto TM, Huhtala H, Iverson GL, Niskakangas T, Öhman J, Helén P. The incidence of chronic subdural hematomas from 1990 to 2015 in a defined Finnish population. J Neurosurg. 2019 Mar 22:1-11. doi: 10.3171/2018.12.JNS183035. [Epub ahead of print] PubMed PMID: 30901751.

[2] Yang W, Huang J. Chronic Subdural Hematoma: Epidemiology and Natural History. Neurosurg Clin N Am. 2017 Apr;28(2):205-210. doi: 10.1016/j.nec.2016.11.002. Epub 2017 Feb 1. Review. PubMed PMID: 28325454

[3] Balser D, Farooq S, Mehmood T, Reyes M, Samadani U. Actual and projected incidence rates for chronic subdural hematomas in United States Veterans Administration and civilian populations. J Neurosurg. 2015 Mar 20:1-7. [Epub ahead of print] PubMed PMID: 25794342; PubMed Central PMCID: PMC4575892.

Q4 Report 2022 – invitation to conference call and audiocast

Stockholm, February 9, 2023 – On Thursday, February 16, at 16.00 CET, IRRAS will host a conference call and an online presentation of its Q4 2022 interim report (which will have been published earlier on February 16 at 08.00 CET). The presentation will be held in English.

Dial-in number to the teleconference will be received by registering on the link below. After the registration you will be provided phone numbers and a conference ID to access the conference:

https://conference.financialhearings.com/teleconference/?id=5005418

The presentation will be webcast and can be accessed from the following web address:

https://ir.financialhearings.com/irras-q4-2022

Speakers: President and CEO Will Martin, Interim CFO Griffen Stapp, and Head of Investor Relations Sten Gustafsson

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on February 9, 2023 at 8:30 (CET).

IRRAS Announces Changed Publication Date for the Q4 2022 Interim Report

Stockholm, Sweden, February 1, 2023 IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced that the publication of the interim report for the period from October to December 2022 (“Q4 2022 Interim Report”) will be published on Thursday, 16 February 2023.

Report Previously Announced Date New Date
Q4 2023 interim report 22 February 2023 16 February 2023

                                                       Financial calendar for 2023

Annual report 2022 27 April 2023
Q1 2023 interim report 17 May 2023
Annual General Meeting 7 June 2023
Q2 2023 interim report 24 August 2023
Q3 2023 interim report 9 November 2023
Q4 2023 interim report 21 February 2024

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on February 1, 2023, at 8:30 (CET).

IRRAS Receives US FDA 510(k) Clearance for its Next Generation IRRAflow Control Unit

Stockholm, December 12, 2022 – IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced that it received regulatory clearance from the United States Food, Drug, and Administration (FDA) to active all of the functionality on the next generation control unit for its flagship product, IRRAflow, the world’s first and only active fluid exchange system.

Earlier this year, IRRAS introduced this next-generation IRRAflow system, which included embedded interactive tutorials, intuitive software with upgraded graphics, refined treatment workflow, and a new drainage collection design, to its customers in the US.  This most recent FDA 510(k) clearance extends the system’s previous FDA clearances and permits the activation of software functionality that connects to the patient’s bedside monitor and openly transmits treatment information to the central nursing station.

The IRRAflow system advances treatment options for patients suffering from intracranial bleeding as the first irrigating drainage system that enables active fluid exchange. IRRAflow combines automated irrigation, controlled drainage, and continuous monitoring of the patient’s intracranial pressure (ICP) into one intelligent system.  Its unique mechanism of action uses recurring irrigation to prevent solid particles from blocking the drainage holes on the catheter tip and to also dilute collected toxic material, making it easier to remove.

“IRRAS prides itself on consistently upgrading its products to better meet the needs of its customers, and the US regulatory clearance of the next generation IRRAflow control unit is the latest example of our team delivering upon that promise,” said Will Martin, President and Chief Executive Officer of IRRAS.  “Our team remains focused upon incorporating customer feedback into our technologies to enhance the user experience and optimize care for their critically ill patients.  Being able to introduce the latest IRRAflow functionality is the exciting next step toward accomplishing our mission to becoming a global leader in the neurocritical space.”

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on December 12, 2022, at 8:00 (CET).

Nomination Committee for the IRRAS 2023 Annual General Meeting

Stockholm, December 6, 2022 – According to the principles for the appointment of the Nomination Committee in IRRAS AB (publ), the Nomination Committee for the annual general meeting 2023 shall be composed of members that represent the three largest shareholders after the end of the third quarter of the year before the AGM is held, together with the chairman of the company’s Board of Directors. The largest shareholders refer to the registered shareholders or otherwise known shareholders after the end of the third quarter.

The composition of the Nomination Committee has now been established, and IRRAS today announced that the Nomination Committee for the annual general meeting 2023 consists of the following persons:

  • Christer Hellström, chairman of the nomination committee, representing Bacara Holdings Limited
  • Philippe Audi, representing Spetses Investments Limited
  • Yana Vlasova, representing Lexington Holding Assets Limited
  • Marios Fotiadis, Chairman of the Board of IRRAS AB

The Nomination Committee’s proposals will be presented in the Notice to the annual general meeting 2023 and on IRRAS’ website, www.irras.com.

Shareholders who wish to submit proposals to the Nomination Committee can do so by sending an e-mail to nomination@irras.com (subject “Nomination Committee”) or by letter posted to IRRAS AB, Attn: IRRAS Nomination Committee, Vasagatan 16, 111 20 Stockholm, Sweden.

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:
Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on December 6, 2022 at 8:30 (CET).

IRRAS Announces Commercial Partnership with Medtronic in the United States for its IRRAflow[®] System

Stockholm, November 14, 2022 – IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced it has signed a Sales Agency Agreement to promote its IRRAflow system in the United States with Medtronic, a global leader in healthcare technology.

During the initial pilot phase of the agreement, Medtronic shall have the exclusive right to promote IRRAflow in a select number of its territories in the United States.  The IRRAS neurocritical education team will closely support the Medtronic sales professionals to train new customers, fulfill customer orders, and support patient treatments within these designated territories. 

In areas of the United States that are not governed by this Sales Agency Agreement, IRRAS’ team of sales professionals will continue to directly promote IRRAflow to stroke center customers. 

“Medtronic is a company that is unsurpassed in its focus on therapies that extend life, restore health, and improve patient outcomes,” said Will Martin, President and Chief Executive Officer of IRRAS. “As the largest medical device company in the world, Medtronic is the ideal partner to accelerate the commercial launch of our IRRAflow system in the world’s largest market.  This partnership will build broader awareness of IRRAS’ cutting-edge technology and will ensure that more patients with intracranial bleeding can receive the latest available advances in treatment.”

At the current time, IRRAS’ previously stated financial targets remain unchanged.  As the partnership with Medtronic matures, IRRAS will assess the impact of the shift in its sales strategy on these targets and will provide all needed updates in a timely fashion.

About the IRRAflow Active Fluid Exchange System

Patients that suffer from intracranial bleeding historically have suffered from subpar clinical outcomes due to the inherent shortcomings of passive drainage catheters that are used to drain excess fluid and remove collected blood within the brain.  Traditional drainage catheters experience unacceptably high rates of complications, such as catheter occlusions, insufficient drainage, and infection, that are well documented in clinical evidence, and the IRRAflow system has been designed to address such shortcomings and advance treatment options for these critically ill patients 

As the only system that enables active exchange of intracranial fluids, IRRAflow combines automated irrigation, controlled drainage, and continuous monitoring of the patient’s intracranial pressure (ICP) within one intelligent system.  IRRAflow’s unique mechanism of action uses recurring irrigation to prevent solid particles from blocking the drainage holes on the catheter tip and also to dilute collected toxic material, making it easier to remove.  This enhanced treatment has been shown to improve patient outcomes and reduced required treatment time across a variety of intracranial pathologies in more than 15 manuscripts published in peer-reviewed journals.

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

This information is considered information that IRRAS is obliged to disclose pursuant to the EU Market Abuse Regulation. The information was released for public disclosure, through the agency of the contact person above, on November 14, 2022, at 18:00 (CET).

 IRRAS Announces Commercial Partnership with Medtronic in the United States for its IRRAflow System

IRRAS AB publishes Interim Report for the period January to September 2022

Third quarter, July – September 2022

  • Net revenue amounted to SEK 11.0 million (6.1).
  • Operating loss (EBIT) amounted to SEK -51.9 million (-27.0).
  • Loss after tax amounted to SEK -50.1 million (-26.9).
  • Earnings per share before and after dilution amounted to SEK -0.14 (-0.34).
     

Period, January – September 2022

  • Net revenue amounted to SEK 29.4 million (15.2).
  • Operating loss (EBIT) amounted to SEK -121.4 million (-93.0).
  • Loss after tax amounted to SEK -120.3 million (-92.9).
  • Earnings per share before and after dilution amounted to SEK -0.73 (-1.30).
     

Significant events during the quarter

Rights issue of MSEK 215 completed

  • IRRAS announced and completed a fully subscribed rights issue that raised MSEK 215 before deduction of costs related to the transaction.

Short-term financing agreement expanded

  • The extension of the bridge loan agreement that was initially signed during Q2 2022 provided an additional MSEK 10 to IRRAS. The entire MSEK 40 bridge loan was repaid with proceeds from the rights issue during Q3.

Enrollment begins in DIVE study as Mt. Sinai Health System in New York City treats its first patients

  • The DIVE study is a single-center clinical trial to evaluate the safety and radiographic outcomes associated with IRRAflow compared to Mt. Sinai’s historic experience with external ventricular drains.  

Significant events after the quarter

IRRAS participates in key neurosurgery conferences

  • IRRAS exhibited at the Congress of Neurological Surgeons (CNS) annual meeting in San Francisco, the Neurocritical Care Society (NCS) annual meeting in San Antonio, and at the European Congress of Neurosurgery in Belgrade, Serbia.

New educational webinar series announced in collaboration with Jacobs Institute and the University of Buffalo Department of Neurosurgery

  • IRRAS announced that Dr. Adnan Siddiqui and the leading neurosurgeons in Buffalo, NY, will host a series of webinars to discuss new treatments for intracranial hemorrhage, including the benefits of utilizing IRRAflow to more effectively clear collected blood from the brain.  This webinar series will enable further peer-to-peer discussion among top neurosurgeons to discuss how IRRAflow has impacted their patients.

The report is available on the company’s website:  https://investors.irras.com/en/reports-presentations.

Q3 Report 2022 – conference call and audiocast
IRRAS will host a conference call and an online presentation of its Q3 2022 interim report on November 10 at 09.00 CET. The presentation will be held in English.

The dial-in numbers for the conference call are:
Sweden: +46 8 50 51 63 86
UK: +44 203 198 4884
US: +1 412 317 6300
PIN code: 8057017#

The presentation will be webcast and can be accessed from the following web address:

https://ir.financialhearings.com/irras-q3-2022

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.  

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com

IRRAS AB (publ) is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

USA
Will Martin
President and CEO

ir@irras.com

Europe

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

This document is considered information that IRRAS is obliged to disclose pursuant to the EU Market Abuse Regulation. The information was released for public disclosure, through the agency of the contact person above, on November 10, 2022, at 8:00 a.m. (CET).

 IRRAS AB (publ) Interim report for January to Sep 2022

Q3 Report 2022 – invitation to conference call and audiocast

Stockholm, November 3, 2022 – On Thursday, November 10, at 09.00 CET, IRRAS will host a conference call and an online presentation of its Q3 2022 interim report (which will have been published earlier on November 10 at 08.00 CET). The presentation will be held in English.

The dial-in numbers for the conference call are:
Sweden: +46 8 50 51 63 86
UK: +44 203 198 4884
US: +1 412 317 6300
Pin code: 8057017#

The presentation will be webcast and can be accessed from the following web address:

https://tv.streamfabriken.com/irras-q3-2022

Speakers: President and CEO Will Martin, Interim CFO Griffen Stapp, and Head of Investor Relations Sten Gustafsson

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on November 3, 2022 at 8:30 (CET).

IRRAS Announces Participation and Data Presentation at the 22nd European Congress of Neurosurgery

Stockholm, October 13, 2022 – IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced it will be exhibiting at EANS 2022, the 22nd European Congress of Neurosurgery, hosted by the European Association of Neurological Societies. After two consecutive years in which the Congress was impacted by the Covid-19 pandemic, the EANS Annual Congress is again being held in person in Belgrade, Serbia, on 16 to 20 October 2022. Attendees of EANS 2022 are encouraged to learn more about IRRAS’ products, including its IRRAflow Active Fluid Exchange system, by visiting IRRAS’ booth #10.

In addition to exhibiting its products for conference participants, clinical data regarding the use of the IRRAflow system to treat intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) will be presented in a case series poster by Dr. Behnam Rezai Jahromi, a neurosurgeon from Helsinki University Hospital. The poster presentation, titled “Active CSF Exchange System for IVH Treatment,” will be available for review, in-person and virtually, for registered participants of EANS.

“My experience utilizing IRRAflow has shown impressive results in clearing out toxic blood in ventricles after patients have experienced ruptured aneurysms and the associated intracranial hemorrhage,” said Dr. Rezai Jahromi. “The combination of the IRRAflow system’s recurring irrigation, when combined with thrombolytic medication, can change the composition of cerebrospinal fluid, accelerate the ability to remove the toxic materials, and improve the clinical outcomes of these critically ill patients.”  

Dr. Rezai Jahromi will also lead an educational session on Tuesday, October 18th, at 1000 CET within the IRRAS booth. During the session, Dr. Rezai Jahromi will present his clinical experience utilizing IRRAflow to treat IVH patients and will also provide an update on the ARCH (Active Removal of Intracerebral Hematoma via active irrigation of ventricular system) clinical trial. 

To learn more about the ARCH clinical trial, click here: https://clinicaltrials.gov/ct2/show/NCT05118997?cond=active+removal&draw=2&rank=1.

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on October 13, 2022, at 8:30 (CET).

IRRAS Announces New Educational Webinar Series in Collaboration with the Jacobs Institute and the University of Buffalo Department of Neurosurgery

Stockholm, October 11, 2022 – IRRAS, a commercial-stage medical technology company with a comprehensive portfolio of innovative products for neurocritical care, today announced the launch of a new educational webinar series, “Exploring the Impact of IRRAflow’s Active Fluid Exchange: Our Early Experience Utilizing IRRAflow for Intracranial Hemorrhage”, with the Jacobs Institute.

During each live webinar, Dr. Adnan Siddiqui, Chief Executive Officer and Chief Medical Officer of the Jacobs Institute, will moderate a panel of neurosurgeon experts in a 60-minute interactive discussion around new treatments for intracranial hemorrhage. Physician panelists and topics will vary with each webinar, but the overall subject will focus on the benefits of utilizing IRRAflow’s active fluid exchange to quickly and efficiently clear blood from the intraventricular space.

During each episode of the webinar series, Dr. Siddiqui and an esteemed group of expert panelists will discuss the historical shortcomings of traditional treatment for patients with intracranial bleeding and how new technological advances, such as IRRAS’ IRRAflow system, expand the options available to treat this challenging patient population. In addition, each physician panelist will discuss their experience incorporating IRRAflow into their clinical practice and share their recently published IRRAflow case reviews and ongoing clinical studies.  

“We are excited to partner with the Jacobs Institute, Dr. Siddiqui, and the University of Buffalo Department of Neurosurgery to bring together leading experts to discuss the evolution in treatment for intracranial bleeding,” said Will Martin, President and CEO of IRRAS. “Dr. Siddiqui and his peers in Buffalo are world-renowned for their contribution to advancing innovation in the treatment of stroke, and we feel that this webinar series will create an ideal learning environment where experts share advice with their peers regarding cutting-edge technology, and lessons learned during clinical practice.”

The IRRAflow Webinar Series
Title: Exploring the Impact of IRRAflow’s Active Fluid Exchange: Our Early Experience Utilizing IRRAflow for Intracranial Hemorrhage
Date: Tuesday, October 25th
Time: 5 pm EST

Moderator: Adnan H. Siddiqui, MD, Ph.D., CEO/CMO of the Jacobs Institute, Professor and Vice Chairman of the University of Buffalo Department of Neurosurgery (UBNS), and Director of Neurosurgical Stroke Service for Kaleida Health

Panelists:

  • Elad Levy, MD, Professor and Chairman of the University of Buffalo Department of Neurosurgery (UBNS), President-Elect of the Congress of Neurological Surgeons, and Co-Director, Gates Stroke Center at Kaleida Health 
  • Jason Davies, MD, Ph.D., Director of Cerebrovascular Microsurgery, Director of Endoscopy, Kaleida Health
  • Ryan Hess, MD, Department of Neurosurgery, Jacobs School of Medicine & Biomedical Science
  • Will Martin, President and CEO of IRRAS

Register Here: https://jacobsinstitute-org.zoom.us/webinar/register/WN_HieJpGtATlO2Z7zfvhYTiQ

About The Jacobs Institute

The Jacobs Institute is a non-profit organization whose mission is to accelerate the development of next-generation technologies in vascular medicine through collisions of physicians, engineers, entrepreneurs, and industry. The JI's vision is to improve the treatment of vascular disease in Western New York and the world, while fostering local economic development. The JI fosters medical collaboration and innovation through partnerships with the University at Buffalo (UB), Kaleida Health, and industry, to be a fitting tribute to the work and memory of Lawrence D. Jacobs, M.D.

To learn more about the Jacobs Institute, please visit our website at: https://jacobsinstitute.org.

About IRRAS

IRRAS is a global medical care company focused on delivering innovative medical solutions to improve the lives of critically ill patients. IRRAS designs, develops, and commercializes neurocritical care products that transform patient outcomes and decrease the overall cost of care by addressing complications associated with current treatment methodologies. IRRAS markets and sells its comprehensive, innovative IRRAflow and Hummingbird ICP Monitoring product lines to hospitals worldwide through its direct sales organization in the United States and select European countries as well as an international network of distribution partners.

IRRAS maintains its headquarters in Stockholm, Sweden, with corporate offices in Munich, Germany, and San Diego, California, USA. For more information, please visit www.irras.com.

IRRAS is listed on Nasdaq Stockholm (ticker: IRRAS).

For more information, please contact:

Sten Gustafsson
Director, Investor Relations
sten.gustafsson@irras.com
+46 102 11 5172

The information was released for public disclosure, through the agency of the contact person above, on October 11, 2022, at 8:30 (CET).

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